This collection is arranged in 9 series: Correspondence, Dante, Dorothy L. Sayers, Events, Wheaton College, Barbara Reynolds Lectures, Ariosto Materials, Publications, and Personal Papers.

The Correspondence series contains General Correspondence arranged chronologically (1954-2000), followed by correspondence with individuals as noted, arranged alphabetically by last name and then chronologically.

The Dante series includes a wide variety of notes, publications, events, and other materials relating to the extensive work Dr. Reynolds did in Dante studies throughout her career. Note that lectures she gave on Dante appear in the Barbara Reynolds Lectures series.

The Dorothy L. Sayers series contains related correspondence, information on Sayers memorials, articles and publications by and about Sayers, material relating to scholarship on Sayers by others, Sayers events, notes on works by Sayers, research materials on people who knew Sayers, and unpublished materials. Researchers should note that the correspondence between Reynolds and Sayers is stored in the Wade's Dorothy L. Sayers Papers, folders 540-565.

The Events series contains related materials to several events Reynolds attended, including: the American Ariosto Centennial Celebration, the Italian Institute, and the Malvern Conference (1991).

The Wheaton College series relates to the time Dr. Reynolds spent at Wheaton College, and her relationships and activities there. It includes materials on the Wade Center authors, correspondence with Wade Center employees, Dr. Reynolds's friendship with Clyde S. Kilby, notes for the Dante Reading Group at Wheaton - led by Reynolds, lectures Reynolds gave at Wheaton, the Certificate of Merit and Doctor of Letters diploma awarded to Reynolds by Wheaton College, some VII materials, and her participation in the dedication of the Wade Center building in 2001. Note that some Wheaton-related photos appear in the Personal Papers series.

The Barbara Reynolds Lectures series includes a variety of lectures given by Dr. Reynolds primarily on the topics of Dante, Dorothy L. Sayers, and Ariosto. Includes notes and lecture transcripts.

The Ariosto Materials series contains notes and articles relating to the life and works of the Italian poet Ludovico Ariosto, primarily known for his romance epic Orlando Furioso, which Dr. Reynolds translated.

The Publications series contains articles by Reynolds, and extensive research materials and correspondence relating to her published works, including her Sayers biography Dorothy L. Sayers: Her Life and Soul, the 4 volumes of collected letters of Dorothy L. Sayers, her translations of Orlando Furioso and Vita Nova, and The Passionate Intellect: Dorothy L. Sayers' Encounter with Dante.

The Personal Papers series includes family correspondence, programs from the memorial service following Reynolds's death, a few publications, a CD, a portrait of Reynolds, and a series of photographs, including some from her visits to Wheaton College, and events with the Dorothy L. Sayers Society.